COVID Treatment - Revision history

Marcin: /* Virus Source Code */

2020-03-21T20:10:48Z

Virus Source Code

← Older revision		Revision as of 20:10, 21 March 2020
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	=Virus Source Code=		=Virus Source Code=
	*Crystal structure - [https://proteopedia.org/wiki/index.php/6lu7]		*Crystal structure - [https://proteopedia.org/wiki/index.php/6lu7]
	*Genetic sequence -		*Genetic sequence - read about it - [https://techcrunch.com/2020/03/19/nvidia-makes-its-gpu-powered-genome-sequencing-tool-available-free-to-those-studying-covid-19/]. While we may know the sequence, we also need to know how the protein folds.

Marcin: /* Mechanisms for Cure */

2020-03-21T19:58:07Z

Mechanisms for Cure

← Older revision		Revision as of 19:58, 21 March 2020
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	*Existing drugs - advantage - testing any of many drugs that are already approved by the FDA as safe. See more about this approach at [https://www.livescience.com/covid-19-treatments-might-exist.html]. Can work by many mechanisms, including inhibition, see below.		*Existing drugs - advantage - testing any of many drugs that are already approved by the FDA as safe. See more about this approach at [https://www.livescience.com/covid-19-treatments-might-exist.html]. Can work by many mechanisms, including inhibition, see below.
	*Competitive inhibition - drug that binds to virus or host site, preventing the disease activity from happening - https://en.wikipedia.org/wiki/Competitive_inhibition		*Competitive inhibition - drug that binds to virus or host site, preventing the disease activity from happening - https://en.wikipedia.org/wiki/Competitive_inhibition

			=Virus Source Code=
			*Crystal structure - [https://proteopedia.org/wiki/index.php/6lu7]
			*Genetic sequence -

Marcin at 19:57, 21 March 2020

2020-03-21T19:57:04Z

← Older revision		Revision as of 19:57, 21 March 2020
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			{{Hint\|These are notes taken by a non-expert in the field (MJ), and thus may not reflect industry-standard consensus or accurate knowledge on the topics involved.}}

	What does COVID treatment require?		What does COVID treatment require?

Marcin: /* Mechanisms for Cure */

2020-03-21T19:55:29Z

Mechanisms for Cure

← Older revision		Revision as of 19:55, 21 March 2020
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	=Mechanisms for Cure=		=Mechanisms for Cure=
	*Existing drugs - advantage - testing any of many drugs that are already approved by the FDA as safe. See more about this approach at [https://www.livescience.com/covid-19-treatments-might-exist.html]		*Existing drugs - advantage - testing any of many drugs that are already approved by the FDA as safe. See more about this approach at [https://www.livescience.com/covid-19-treatments-might-exist.html]. Can work by many mechanisms, including inhibition, see below.
			*Competitive inhibition - drug that binds to virus or host site, preventing the disease activity from happening - https://en.wikipedia.org/wiki/Competitive_inhibition

Marcin at 19:53, 21 March 2020

2020-03-21T19:53:44Z

← Older revision		Revision as of 19:53, 21 March 2020
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	=Mechanism of Infection=		=Mechanism of Infection=
	*Here is one point of view - [https://www.livescience.com/covid-19-treatments-might-exist.html]		*Here is one point of view - [https://www.livescience.com/covid-19-treatments-might-exist.html]

			=Mechanisms for Cure=
			*Existing drugs - advantage - testing any of many drugs that are already approved by the FDA as safe. See more about this approach at [https://www.livescience.com/covid-19-treatments-might-exist.html]

Marcin at 19:41, 21 March 2020

2020-03-21T19:41:40Z

← Older revision		Revision as of 19:41, 21 March 2020
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	=Transmission=		=Transmission=
	*Wells evaporation-falling curve - 100 micron droplets dry out and nuclei fall to the ground within a few seconds, with max at 160 microns after which they do not dry but fall to the ground more quickly due to heavier weight. - [https://www.ncbi.nlm.nih.gov/books/NBK143281/]. Summary - if airflows exist (even convection from higher body temperature) - contamination may occur to other patients, and even large distances if air movement is present (wind, doors opening, etc).		*Wells evaporation-falling curve - 100 micron droplets dry out and nuclei fall to the ground within a few seconds, with max at 160 microns after which they do not dry but fall to the ground more quickly due to heavier weight. - [https://www.ncbi.nlm.nih.gov/books/NBK143281/]. Summary - if airflows exist (even convection from higher body temperature) - contamination may occur to other patients, and even large distances if air movement is present (wind, doors opening, etc).

			=Mechanism of Infection=
			*Here is one point of view - [https://www.livescience.com/covid-19-treatments-might-exist.html]

Marcin: /* Transmission */

2020-03-21T19:39:29Z

Transmission

← Older revision		Revision as of 19:39, 21 March 2020
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	=Transmission=		=Transmission=
	*Wells evaporation-falling curve - 100 micron droplets dry out and nuclei fall to the ground within a few seconds, with max at 160 microns after which they do not dry but fall to the ground more quickly due to heavier weight. - [https://www.ncbi.nlm.nih.gov/books/NBK143281/]		*Wells evaporation-falling curve - 100 micron droplets dry out and nuclei fall to the ground within a few seconds, with max at 160 microns after which they do not dry but fall to the ground more quickly due to heavier weight. - [https://www.ncbi.nlm.nih.gov/books/NBK143281/]. Summary - if airflows exist (even convection from higher body temperature) - contamination may occur to other patients, and even large distances if air movement is present (wind, doors opening, etc).

Marcin: Created page with "What does COVID treatment require? =Transmission= *Wells evaporation-falling curve - 100 micron droplets dry out and nuclei fall to the ground within a few seconds, with max..."

2020-03-21T19:37:11Z

Created page with "What does COVID treatment require? =Transmission= *Wells evaporation-falling curve - 100 micron droplets dry out and nuclei fall to the ground within a few seconds, with max..."

New page

What does COVID treatment require?

=Transmission=
*Wells evaporation-falling curve - 100 micron droplets dry out and nuclei fall to the ground within a few seconds, with max at 160 microns after which they do not dry but fall to the ground more quickly due to heavier weight. - [https://www.ncbi.nlm.nih.gov/books/NBK143281/]