Antibodies: Difference between revisions
Jump to navigation
Jump to search
| Line 9: | Line 9: | ||
*Recombinant DNA - genetic engineering of DNA that does not yet exist in nature - [https://en.wikipedia.org/wiki/Recombinant_DNA] | *Recombinant DNA - genetic engineering of DNA that does not yet exist in nature - [https://en.wikipedia.org/wiki/Recombinant_DNA] | ||
*Recombinant antibodies - [''ecombinant antibodies are produced in vitro by cloning antibody genes for immune-specific heavy and light antibody chains into high-yield expression vectors'' - [https://www.abcam.com/primary-antibodies/recombinant-antibodies] | *Recombinant antibodies - [''ecombinant antibodies are produced in vitro by cloning antibody genes for immune-specific heavy and light antibody chains into high-yield expression vectors'' - [https://www.abcam.com/primary-antibodies/recombinant-antibodies] | ||
*Serological (antibody) vs PCR tests for COVID - [https://www.healthline.com/health-news/how-antibody-testing-can-help-us-fight-covid-19#What-is-an-immunity-test?] | |||
Revision as of 02:31, 6 April 2020
- Antibodies are blood proteins that kill cellular intruders (disease) - [1]
- How do you culture antibodies? Via hybridomas - [2]
Companies Working on It
- GigaGen - [3] - uses single-cell sequencing to “capture and recreate” whole libraries of antibodies from recovered COVID-19 patients. The company can then choose which of those antibodies to turn into recombinant polyclonal antibody treatments
Definitions
- Antigen. [4] - ex: a virus.
- Recombinant DNA - genetic engineering of DNA that does not yet exist in nature - [5]
- Recombinant antibodies - [ecombinant antibodies are produced in vitro by cloning antibody genes for immune-specific heavy and light antibody chains into high-yield expression vectors - [6]
- Serological (antibody) vs PCR tests for COVID - [7]