COVID Treatment: Difference between revisions
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{{Hint|These are notes taken by a non-expert in the field (MJ), and thus may not reflect industry-standard consensus or accurate knowledge on the topics involved.}} | |||
What does COVID treatment require? | What does COVID treatment require? | ||
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*Existing drugs - advantage - testing any of many drugs that are already approved by the FDA as safe. See more about this approach at [https://www.livescience.com/covid-19-treatments-might-exist.html]. Can work by many mechanisms, including inhibition, see below. | *Existing drugs - advantage - testing any of many drugs that are already approved by the FDA as safe. See more about this approach at [https://www.livescience.com/covid-19-treatments-might-exist.html]. Can work by many mechanisms, including inhibition, see below. | ||
*Competitive inhibition - drug that binds to virus or host site, preventing the disease activity from happening - https://en.wikipedia.org/wiki/Competitive_inhibition | *Competitive inhibition - drug that binds to virus or host site, preventing the disease activity from happening - https://en.wikipedia.org/wiki/Competitive_inhibition | ||
=Virus Source Code= | |||
*Crystal structure - [https://proteopedia.org/wiki/index.php/6lu7] | |||
*Genetic sequence - read about it - [https://techcrunch.com/2020/03/19/nvidia-makes-its-gpu-powered-genome-sequencing-tool-available-free-to-those-studying-covid-19/]. While we may know the sequence, we also need to know how the protein folds. | |||
Latest revision as of 20:10, 21 March 2020
Hint: These are notes taken by a non-expert in the field (MJ), and thus may not reflect industry-standard consensus or accurate knowledge on the topics involved.
What does COVID treatment require?
Transmission
- Wells evaporation-falling curve - 100 micron droplets dry out and nuclei fall to the ground within a few seconds, with max at 160 microns after which they do not dry but fall to the ground more quickly due to heavier weight. - [1]. Summary - if airflows exist (even convection from higher body temperature) - contamination may occur to other patients, and even large distances if air movement is present (wind, doors opening, etc).
Mechanism of Infection
- Here is one point of view - [2]
Mechanisms for Cure
- Existing drugs - advantage - testing any of many drugs that are already approved by the FDA as safe. See more about this approach at [3]. Can work by many mechanisms, including inhibition, see below.
- Competitive inhibition - drug that binds to virus or host site, preventing the disease activity from happening - https://en.wikipedia.org/wiki/Competitive_inhibition