Non 24-Hour Sleep Phase Disorder

• [1] - Having unstructured or irregular daily routines, bad sleeping habits, and poor exposure to sunlight on a consistent basis can all be factors in the development of this disorder.
• This is a thorough explanation of wake-sleep patterns - including SCN, melatonin, melanopsin, blindness effects, homeostasis vs extra alertness hormones, and more. [2]
  • Some people are hypersensitive to waking effects of light, some are subsensitive.
  • There is circadian rhythm and a cellular clock. Both must be correlated.
  • There is an internal clock, typically 24.2 hours, and light effects. Light reduces internal clock, to entrain with 24 hour cycles.
  • Muscle cells, in vitro, showed N24 on the cellular level (levels of activity)
  • There is an extreme evening chronotype and free-running N24. Existence of Extreme Evening Chronotype means that there are other factors contributing to clinical N24.
  • 'Deficiency in homeostatic drive for sleep'
  • Delayed sleep phase disorder- when you go to bed late and wake late, regularly. Sleep in on weekends.
  • Why not delay bedtime to get to normal cycle? Why not make bedtime early? Advantage + disadvantage? In former, we get lazy. In latter, we get sleep deprived. Which is better? Which case is true?
  • Extreme evening chronotype - you go to bed late. Make it up on weekends.
  • Social jetlag - when your sleep time is different than others
  • Circadian Sleep Disorders Network - [3]
  • Idiopathic hypersomnia - like N24, but it is caused by the sleep time being longer, with constant wake time.